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Search Results for " rrna synthesis "

7

Compounds

Cat No. Product Name Synonyms Targets
T35648 4-Thiouridine Others
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl...
T2100 CX-5461 DNA/RNA Synthesis
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.
T22297 Clindamycin hydrochloride monohydrate Clindamycin alcoholate Antibiotic
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra...
T61121 NusB-IN-1
NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1].
T64150 CX-5461 dihydrochloride
CX-5461 dihydrochloride is a potent, orally active inhibitor of Pol I-mediated rRNA synthesis that acts on HCT-116 cells (IC50: 142 nM), A375 cells (IC50: 113 nM) and MIA PaCa-2 cells (IC50: 54 nM), and to a lesser exten...
T69908 Pidnarulex HCl
Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhi...
T37154 7-Methylguanosine 5'-diphosphate sodium
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1].
TargetMol