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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35648 | 4-Thiouridine | Others | |
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl... | |||
T2100 | CX-5461 | DNA/RNA Synthesis | |
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA. | |||
T22297 | Clindamycin hydrochloride monohydrate | Clindamycin alcoholate | Antibiotic |
Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra... | |||
T61121 | NusB-IN-1 | ||
NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1]. | |||
T64150 | CX-5461 dihydrochloride | ||
CX-5461 dihydrochloride is a potent, orally active inhibitor of Pol I-mediated rRNA synthesis that acts on HCT-116 cells (IC50: 142 nM), A375 cells (IC50: 113 nM) and MIA PaCa-2 cells (IC50: 54 nM), and to a lesser exten... | |||
T69908 | Pidnarulex HCl | ||
Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhi... | |||
T37154 | 7-Methylguanosine 5'-diphosphate sodium | ||
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1]. |